Nucific Bio X4 Probiotics for weight loss review

Editor’s note:- Overall, a good probiotic, but not the best for weight loss. For best probiotic for weight loss, I currently recommend P3OM.  Here are comprehensive reasons why I think P3-OM is best probiotic for fixing digestion as well as weight loss.

Another thing with Biox4 is they use ingredients like green tea, caralluma but their dosage is quite low in the product. Their inclusion seems to be more of a marketing ploy. Our take is – if you want to go for a natural thermogenic like green tea based fat burner, make sure the ingredients are in enough quantity eg. in Instant Knockout, or Phen375 which I recommend over Bio x4. If you specifically want a probiotics for weight loss, I recommend P3OM.

Bio X4 is a weight-loss probiotic supplement. It comes in capsule form. They instruct users to take it daily for maximum fat-burning and digestive health.

The formula consists of four blends that the manufacturer claims work together to support optimal digestive health, increased calorie-burning and accelerated weight reduction. It also promises to help cut cravings and suppress appetite.

Bio X4 is available online only. Its manufacturer is based in the United States.

Nucific Bio X4 is marketed as a four-in-one weight management probiotic that has been manufactured by a company that goes by the same name ‘Nucific‘, that is based in California, United States.

According to the manufacturer, Nucific Bio X4 uses potent ingredients that have been clinically tested and proven to give quality results. It has been created to help people with digestion problems, bowel irregularity, weight issues as well as those who want to strengthen their immune system.


Bio X4 relies on four-ingredient blends to potentially support better digestion, control food cravings, increase energy and promote weight loss. The formulas include a:

Probiotic blend
Digestive enzyme blend
Weight management blend
Craving control blend

Probiotic blend (Lactobacillus Blend):

By taking 3 capsules per day, you cumulatively ingest 39 billion CFUs.

L. Acidophilus
L. Acidophilus
L. Rhamnosus
L. Plantarum
Bifidobacterium Blend:
B. Lactis
B. Animalis

Digestive Enzyme Blend:

Amylase (from Aspergilus Oryzae)
Lipase (from Rhizopus Oryzae)

Weight Management Blend:

Green tea Extract (50% EGCG)

Craving Control Blend:

Caralluma Fimbriata Extract


Promotes optimal digestive health.
The manufacturer offers package deals.
Improves bowel regularity.
Enhances immune system health.
Supports higher energy levels.
Gluten-, allergen-, and lactose-free.
90-day money-back guarantee.
Eco-friendly packaging.
Third-party lab tests.
Transparent about board members and their qualifications.
Useful health blog on the official website.


  • It is fairly expensive.
  • Weight loss ingredients seem to be low in quantity
  • You must take it on a regular basis to experience maximal effects. Some users may have trouble remembering to take the capsules three times a day.
  • Only available online.

Does it work?

The product has mixed reviews.

If it were to do some research and see what people are saying about the side effect that this supplement has, many of them reported that they felt a little bloating after taking Nucific Bio x4. And this is a confusing thing because is supposed that Nucific Biox4 should fight stuff like bloating or gas.

Another customer said that precisely after starting taking Nucific Bio x4 he started developing persistent loose stools with a lot of gas. Another one, who only took one pill for breakfast says that is already feeling jittery and edgy.

On the other side, there are also many users who say they felt excellent after taking the first pills and no severe side effects occurred. They say that no bloating or stomach problems happened and if the pills are taking correctly, they won`t make indigestion.

But as usual, the opinions are split. We can`t know for sure which are true and which aren’t. So, what remains to be done? It’s evident that the product acts differently, according to the person`s body. The side effects aren’t severe, are just unpleasant, and after a few days of taking the supplements, they might disappear.


Overall Nucific BIO X4[1] is a good probiotic supplement that combines 4 proven nutrients to support digestive health and weight loss management. The probiotics in BIO X4 is a 4-in-1 Weight Management Probiotic help restore the ideal balance in your gut, supporting immune health and promoting regular bowel movements, while the Griffonia Seed Extract (5-­HTP) is included in the formula for its appetite suppressing properties.

But, similar to other probiotic supplements like ProBioslim, the product isn’t good enough.

This weight management probiotic contains a proprietary Digestive Enzyme blend that eases digestion of proteins, fats and carbs, but also Green Tea to boost metabolism. When you combine these 4 nutrients, you get the perfect digestive support that immediately starts invigorating your body from the inside out.

However, the quantities of weight loss ingredients like Green tea and Caralluma Fimbriata are too small to show any effect.

Moreover, there are better probiotic products out there that provide good value for money and backed by medical authority and experts. I recommend P3 OM and ProBiotic 40.

There is little doubt that Bio X4 is a popular nutritional probiotic and weight control supplement among consumers. Most of its ingredients have a historical, worldwide use for weight loss and health.

If you’re at the point you want to lose those extra pounds, consider adding a supplement containing clinically tested ingredients to the mix. Also following a real-foods based gut-friendly diet is recommended. I also recommend Lean Optimizer and Smoothie Diet.